Double-Stranded DNA Antibodies

Alternative Names/Synonyms	Anti-dsDNA Antibody
Laboratory	Core Laboratory & Transfusion Medicine
Sub-section	Biochemistry
Specimen Type	Blood
Test Code	DNA2

Ordering Instructions, Requisition

Can be ordered and done as part of Connective Tissue Disease (CTD+) Screen.

Clinical Significance (If applicable)

Aiding in diagnosis of systemic lupus erythematosus.

Specimen Requirements (Sample Type)

Serum

Specimen Requirements (Volume (mL))

0.5 mL

Specimen Requirements (Tube Type)

Serum (Gold SST)
Collection Containers – Tube Types

Collection Requirements

Collection Instructions

Storage / Shipment Details

Freeze for shipment or if assay not completed within 10 days.

Sample Stability

Room Temperature: 48 hours

Fridge: 10 days @ 2-8°C

Freezer: 6 months @ -20°C

Cause for Rejection

Specimen Acceptability and Transport Guidance

Instrument, Methodology

BIO-FLASH, immunoassay

Test Availability

Weekdays

Routine Turnaround Time

1 week

Reference Ranges

Negative: < 20 IU/mL
Indeterminate: 27 - 35 IU/mL
Positive: > 35 IU/mL

In case of discrepancies, always interpret results using reference ranges as stated on laboratory reports and/or electronic patient chart.

Laboratory Contact Information

416-586-4800 extension 4688

Ordering Practices

Can be ordered alone or as part of the Connective Tissue Disease reflex panel.