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Double-Stranded DNA Antibodies

Alternative Names/Synonyms	Anti-dsDNA Antibody
Laboratory	Core Laboratory & Transfusion Medicine
Sub-section	Biochemistry
Specimen Type	Blood
Test Code	DNA2

Ordering Instructions, Requisition

Can be ordered and done as part of Connective Tissue Disease (CTD+) Screen.

Clinical Significance

Aiding in diagnosis of systemic lupus erythematosus.

Specimen Requirements (Sample Type)

Serum

Specimen Requirements (Volume (mL))

0.5 mL

Specimen Requirements (Tube Type)

Serum (Gold SST)
Collection Containers – Tube Types

Collection Requirements

Blood Collection Instructions

Storage / Shipment Details

Freeze for shipment or if assay not completed within 10 days.

Sample Stability

Room Temperature: 48 hours

Fridge: 10 days @ 2-8°C

Freezer: 6 months @ -20°C

Cause for Rejection

Specimen Acceptability and Transport Guidance

Instrument, Methodology

BIO-FLASH, immunoassay

Test Availability

Weekdays

Routine Turnaround Time

1 week

Reference Ranges

Negative: < 20 IU/mL
Indeterminate: 27 - 35 IU/mL
Positive: > 35 IU/mL

In case of discrepancies, always interpret results using reference ranges as stated on laboratory reports and/or electronic patient chart.

Laboratory Contact Information

416-586-4800 extension 4688

Ordering Practices

Can be ordered alone or as part of the Connective Tissue Disease reflex panel.