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Endometrial Cancer Panel
Alternative Names/Synonyms
SGT, Somatic Genetic Testing, CTNNB1, KRAS, PIK3CA, POLE, PTEN, TP53, Endometrium
Laboratory
Diagnostic Medical Genetics
Sub-section
Advanced Molecular Diagnostics
Specimen Type
Fixed Tissue - Formalin Fixed Paraffin Embedded
Test Code
M3ENT1
Ordering Instructions, Requisition
https://www.sinaihealth.ca/media/20281/download?inline
Supporting Documents
Somatic Genetic Testing Reference Sequences
Clinical Significance
Please refer to Genetic Testing Program | Cancer Care Ontario
https://www.cancercareontario.ca/en/guidelines-advice/treatment-modality/pathology-laboratory-testing/genetic-testing-resources
Specimen Requirements (Sample Type)
Formalin Fixed Paraffin Embedded Tissue Block
Specimen Requirements (Volume (mL))
Blocks are preferred.
If submitting slides:
6 x 10um on plain slides + 1 H&E AND 10um curls. Super Clean cutting in 1.5 mL tube
Paraffin Section Cutting Instructions
Storage / Shipment Details
Room Temperature. Must not be refrigerated frozen or exposed to heat.
Cause for Rejection
Specimen Acceptability and Transport Guidance
Test Availability
Routine only; Monday to Friday
Routine Turnaround Time
2 weeks
Laboratory Contact Information
molecularlab.MSH@sinaihealth.ca
Gene(s)
CTNNB1, KRAS, PIK3CA, POLE, PTEN, TP53
Sample Processing / Delivery
Samples received and processed Monday to Friday 8:00 am - 5:00 pm
Funded for patients with OHIP
Yes
Disease/Body Site
Endometrium; Indications outlined by Ontario Health (formerly Cancer Care Ontario); see link in Clinical Significance section