Fetal Aneuploid Testing, Prenatal

Rapid Aneuploid Detection, RAD, QF-PCR, QF
Diagnostic Medical Genetics
Cytogenetics
Prenatal Samples
ANEUFAST

Supporting Documents

Aneuploidy studies
Chromosomes 13, 18, 21, X and Y
Chromosomal abnormalities, Fertility/Reproductive
Amniotic Fluid, Chorionic Villi sample (CVS), Fetal Fluid, Fetal Urine or Fetal Blood Sample
Amniotic Fluid: At least 25 mL;
CVS at least 25 mg;
If sending cultures: 2 x T25 flasks
Sterile container

3 to 5 mL of maternal blood in EDTA (lavender) tube must accompany all CVS specimens
(for MCC Testing)
Do not refrigerate, freeze or expose to heat
Send to lab immediately
QF-PCR
Routine; Monday to Friday
3-5 days
cytogeneticlab.MSH@sinaihealth.ca
If QF-PCR is done at an external centre:
Referring Center must fax RAD results ASAP to MSH (fax: 416-586-8395)
Note: Microarray will only be initiated upon receipt of QF-PCR results.
1. If QF-PCR results are normal then microarray is performed and reported to referring center.
2. If maternal cell contamination is detected then referring center will be notified to send cultured cells to MSH for microarray.
If sending from outside of the hospital: Email the lab at cytogeneticlab.MSH@sinaihealth.ca with courier name and courier tracking #
Associated costs will be billed back to the institution
Yes