Fetal Aneuploid Testing, Prenatal

Alternative Names/Synonyms	Rapid Aneuploid Detection, RAD, QF-PCR, QF
Laboratory	Diagnostic Medical Genetics
Sub-section	Cytogenetics
Specimen Type	Prenatal Samples
Test Code	ANEUFAST

Ordering Instructions, Requisition

https://www.mountsinai.on.ca/care/pathology/laboratory-forms-and-requisitions/cytogenetics-requisition-prenatal-v3-fillable-aoda.pdf

Supporting Documents

Algorithm for Prenatal Testing

Other Information

If sending from outside of the hospital: Email the lab at cytogeneticlab.MSH@sinaihealth.ca with courier name and courier tracking #

Specimen Requirements (Sample Type)

Amniotic Fluid, Chorionic Villi sample (CVS), Fetal Fluid, Fetal Urine or Fetal Blood Sample

Specimen Requirements (Volume (mL))

Amniotic Fluid: At least 25 mL;
CVS at least 25 mg;
If sending cultures: 2 x T25 flasks

Specimen Requirements (Tube Type)

Sterile container

Collection Requirements

3 to 5 mL of maternal blood in EDTA (lavender) tube must accompany all CVS specimens
(for MCC Testing)

Storage / Shipment Details

Do not refrigerate, freeze or expose to heat

Sample Stability

Send to lab immediately

Cause for Rejection

Specimen Acceptability and Transport Guidance

Instrument, Methodology

QF-PCR

Test Availability

Routine; Monday to Friday

Routine Turnaround Time

3-5 days

Laboratory Contact Information

cytogeneticlab.MSH@sinaihealth.ca

Special Instructions

If QF-PCR is done at an external centre:
Referring Center must fax RAD results ASAP to MSH (fax: 416-586-8395)
Note: Microarray will only be initiated upon receipt of QF-PCR results.
1. If QF-PCR results are normal then microarray is performed and reported to referring center.
2. If maternal cell contamination is detected then referring center will be notified to send cultured cells to MSH for microarray.

Billing Information

Associated costs will be billed back to the institution

Funded for patients with OHIP

Yes