Fibrinogen is a plasma protein that is converted from a soluble protein to an insoluble polymer by the action of thrombin, resulting in the formation of a fibrin clot.
The 9:1 blood/citrate ratio must be kept constant. Adjustments for the amount of anticoagulant should be made when the hematocrit is abnormal (above 55%). Mix immediately to prevent clotting.
Collection Instructions
Send whole blood sample(s) at room temperature as soon as possible.
If specimens cannot be shipped immediately, centrifuge and separate plasma within 1 hour of collection, send frozen plasma on dry ice
Adult: 1.50-4.20 g/L
Full-term Infant at Birth: 1.67-3.99 g/L
Premature Infant of 30 to 36 Weeks gestational age: 1.50-3.73 g/L
Premature Infant of < 28 weeks gestational age: 0.7-3.8 g/L In case of discrepancies, always interpret results using reference ranges as stated on laboratory reports and/or electronic patient chart.