Menu
Home
Print
HER2 Fluorescence in Situ Hybridization (Stomach/Esophagus)
Alternative Names/Synonyms
FISH, HER2 FISH, HER2 ISH
Laboratory
Anatomical Pathology
Sub-section
FISH
Test Code
Group Test: HER2GAF
Ordering Instructions, Requisition
In-house: Reflex test following 2+ HER2 IHC score
https://www.mountsinai.on.ca/care/pathology/laboratory-forms-and-requisitions/pathology-consult-requisitionConsult:
Supporting Documents
Ontario Health Guidelines
Clinical Significance (If applicable)
Reflex HER2 FISH testing in stomach/esophageal cancer determines HER2 status, guiding targeted therapy.
Specimen Requirements (Sample Type)
Formalin fixed paraffin embedded block or tissue sections cut at 4 microns mounted on charged or coated slides.
Collection Requirements
Fixation between 6-72 hours
Storage / Shipment Details
Room temperature (block/unstained slide)
Cause for Rejection
Specimen Acceptability and Transport Guidance
Instrument, Methodology
Dako Omnis
References
2016 HER2 Testing in Gastroesophagoeal Adenocarcinoma ASCO/CAP Guidelines:
https://pubmed.ncbi.nlm.nih.gov/27841667/
Test Availability
Monday to Friday; 8 am - 4 pm
Routine Turnaround Time
Typically 7 days, with a maximum of 14 days
Reference Ranges
Please refer directly to the Pathology Report
Laboratory Contact Information
416-586-4800
Extension 4481 or 3813
Ordering Practices
Reflex testing following 2+ HER2 IHC score
© 2024 Sinai Health. All rights reserved.