Hepatitis D – serology

Alternative Names/Synonyms	Serologic detection of antibodies (IgG) against the Hepatitis D virus
Laboratory	Microbiology
Sub-section	Serology
Specimen Type	○ Serum ○ Plasma

Other Information

○ Testing will only be performed on HBsAg positive samples
○ Anti-HDV positive specimens are automatically reflexed to HDV RNA testing, dependent on sample volume.

Specimen Requirements (Tube Type)

○ Serum: serum separator tube (clotted blood)
○ Plasma: EDTA-blood tube (lavender top)

Collection Requirements

○ Decontaminate skin with 70% alcohol followed by iodine or chlorhexidine, collect at least 5 mL of blood

Sample Stability

Refer to section Sample Processing / Delivery

Referral Laboratory

PHOL

Routine Turnaround Time

○ 15 to 21 days

Laboratory Contact Information

416-586-4800 extension 4521

Approval Required

Sample Processing / Delivery

○ Label specimen container. Place specimens in biohazard bag and seal.

○ Specimens should be stored and transported to the UHN/SH Microbiology Laboratory at refrigeration temperature (2-8˚C) immediately after collection

○ The specimen will be referred to the Public Health Ontario Laboratory for testing. PHOL will refer the specimen to NML.