Influenza virus – susceptibility testing (genotyping)

Molecular detection of influenza virus susceptibility to oseltamivir or zanamivir
Microbiology
Virology
○ Any clinical specimens submitted for PCR testing (0,5 mL

Other Information

○ Testing will only be performed by NML if clinically indicated
○ Clinical indications for influenza susceptibility testing include: influenza infection developing during or post-antiviral treatment for influenza, severely ill patients not responding to therapy, fatalities in influenza positive individual after antiviral therapy administered, persistent viral shedding (PCR positive) for more than 7 days after therapy, recent travel history to an area where resistance is endemic in a confirmed influenza A case

Refer to section Sample Processing / Delivery

PHOL

○ 14 days

416-586-4800 extension 4545

YES

○ Label specimen container. Place specimens in biohazard bag and seal.

○ Specimens should be stored and transported to the UHN/SH Microbiology Laboratory at refrigeration temperature (2-8˚C)

○ UHN/Sinai Microbiology Laboratory will refer the original specimen to the National Microbiology or Public Health Ontario Laboratory for testing