MLH1 Promoter Methylation

Alternative Names/Synonyms	Methylation, MLH1
Laboratory	Diagnostic Medical Genetics
Sub-section	Advanced Molecular Genetics
Specimen Type	Fixed Tissue - Formalin Fixed Paraffin Embedded
Test Code	MPMET

Clinical Significance (If applicable)

Please refer to Genetic Testing Program | Cancer Care Ontario
https://www.cancercareontario.ca/en/guidelines-advice/treatment-modality/pathology-laboratory-testing/genetic-testing-resources

Formalin Fixed Paraffin Embedded Tissue Block

Blocks are preferred.

If submitting slides:
6 x 10um on plain slides + 1 H&E

Room Temperature. Must not be refrigerated frozen or exposed to heat.

STAT, Routine; Monday to Friday

3 weeks

molecularlab.MSH@sinaihealth.ca

MLH1

Samples received and processed Monday to Friday 8:00 am - 5:00 pm

Yes

Multiple Disease Sites; Indications outlined by Ontario Health (formerly Cancer Care Ontario); see link in Clinical Significance section