Measles – serology

Alternative Names/Synonyms	Serologic detection of measles virus antibodies (IgG and/or IgM)
Laboratory	Microbiology
Sub-section	Serology
Specimen Type	○ Whole blood ○ Serum

Other Information

○ IgG testing will be performed by PHOL on all measles immunity serology requests.
○ Measles IgG and IgM will be performed on diagnostic requests only, with relevant clinical history.
○ Collect the acute sample within 7 days after the onset of rash. Collect the convalescent sample minimum 7-10 days after the acute, preferably 10-30 days after acute.

Specimen Requirements (Tube Type)

○ Serum separator tube (clotted blood) (min volume 5 mL)

Collection Requirements

○ Decontaminate skin with 70% alcohol followed by iodine or chlorhexidine, collect at least 5 mL of blood

Sample Stability

Refer to section Sample Processing / Delivery

Referral Laboratory

PHOL

Routine Turnaround Time

○ Up to 5 days

Laboratory Contact Information

416-586-4800 extension 4556

Approval Required

Sample Processing / Delivery

○ Label specimen container. Place specimens in biohazard bag and seal.

○ Specimens should be stored and transported to the UHN/SH Microbiology Laboratory at refrigeration temperature (2-8˚C) immediately after collection.

○ The specimen will be referred to the Public Health Ontario Laboratory for testing