NTRK Directed Therapy Panel

Alternative Names/Synonyms	SGT, Somatic Genetic Testing, NTRK1, NTRK2, NTRK3 (fusions)
Laboratory	Diagnostic Medical Genetics
Sub-section	Advanced Molecular Diagnostics
Specimen Type	Fixed Tissue - Formalin Fixed Paraffin Embedded
Test Code	M2NTT1

Please refer to Genetic Testing Program | Cancer Care Ontario Please refer to Genetic Testing Program | Cancer Care Ontario

https://www.cancercareontario.ca/en/guidelines-advice/treatment-modality/pathology-laboratory-testing/genetic-testing-resources

Formalin Fixed Paraffin Embedded Tissue Block

Blocks are preferred.

If submitting slides:
6 x 10um on plain slides + 1 H&E AND 10um curls. Super Clean cutting in 1.5 mL tube

Room Temperature. Must not be refrigerated frozen or exposed to heat.

Routine only; Monday to Friday

2 weeks

molecularlab.MSH@sinaihealth.ca

NTRK1, NTRK2, NTRK3 (fusions)

Samples received and processed Monday to Friday 8:00 am - 5:00 pm

Yes

NTRK Directed Therapy; Indications outlined by Ontario Health (formerly Cancer Care Ontario); see link in Clinical Significance section