Rabies - serology
| Serologic detection of antibodies to Rabies viruses | |
| Microbiology | |
| Serology | |
| ○ Whole blood ○ Serum ○ CSF |
Other Information
○ Testing is only performed to determine immunity to rabies in those who have been previously vaccinated. PHOL does not perform diagnostic testing for rabies. Serum and CSF samples for diagnostic purposes are analyzed at NML.
○ For saliva, nuchal skin biopsy and post-mortem brain tissue rabies testing, contact CFIA in Ottawa: https://www.canadianveterinarians.net/rabies/EN/Documents/5_HUMAN%20SPECIMENS%20v1%202014.pdf
○ For saliva, nuchal skin biopsy and post-mortem brain tissue rabies testing, contact CFIA in Ottawa: https://www.canadianveterinarians.net/rabies/EN/Documents/5_HUMAN%20SPECIMENS%20v1%202014.pdf
○ Serum separator tube (min volume 5 mL)
○ CSF: sterile container (2 mL)
○ CSF: sterile container (2 mL)
Blood:
○ Decontaminate skin with 70% alcohol followed by iodine or chlorhexidine, collect at least 5 mL of blood.
CSF:
○ Decontaminate skin, collect at least 2 mL of CSF by lumbar puncture.
○ Decontaminate skin with 70% alcohol followed by iodine or chlorhexidine, collect at least 5 mL of blood.
CSF:
○ Decontaminate skin, collect at least 2 mL of CSF by lumbar puncture.
Refer to section Sample Processing / Delivery
PHL
○ Up to 7 days from receipt at PHO laboratory
○ Up to 30 days from receipt at NML
○ Up to 30 days from receipt at NML
416-586-4800 extension 4432
YES
○ Label specimen container. Place specimens in biohazard bag and seal.
○ Specimens should be transported to the UHN/SH Microbiology Laboratory ASAP after collection at refrigeration temperature (2-8˚C).
○ The specimen will be referred to the Public Health Ontario Laboratory for testing
○ Specimens should be transported to the UHN/SH Microbiology Laboratory ASAP after collection at refrigeration temperature (2-8˚C).
○ The specimen will be referred to the Public Health Ontario Laboratory for testing