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Soft Tissue and Bone: Gastrointestinal Stromal tumours (GIST) Biomarker Testing, SDHB
Alternative Names/Synonyms
Solid Tumour Biomarker Testing, SDHB
Laboratory
Anatomical Pathology
Sub-section
Surgical Pathology
Ordering Instructions, Requisition
Pathology Consultation and Biomarker Requisition
https://www.mountsinai.on.ca/care/pathology/laboratory-forms-and-requisitions/pathology-consult-requisition
Clinical Significance (If applicable)
Reflex testing on newly diagnosed CD117 (cKIT) positive Gastrointestinal Stromal tumours (GIST).
Biomarkers: SDHB on negative molecular results.
Specimen Requirements (Sample Type)
Formalin fixed paraffin embedded block or tissue sections cut at 4 microns mounted on "Superfrost Plus" charged slides.
Cause for Rejection
Specimen Acceptability and Transport Guidance
Instrument, Methodology
Dako Omnis
References
https://www.cancercareontario.ca/en/guidelines-advice/treatment-modality/pathology-laboratory-testing/genetic-testing-resources
Test Availability
Monday to Friday; 8 am to 5 pm
Reference Ranges
Please refer directly to the Pathology Report
Laboratory Contact Information
Tel: (416) 586-4800 extension 4457
Fax: (416) 586-8628
Email: PLMconsults@sinaihealth.ca
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