Soft Tissue and Bone Biomarker Testing, Copy Number MDM2
FISH, MDM2 FISH, MDM2 ISH, MDM2 Fluorescence in Situ Hybridization, CNV, Solid Tumour Biomarker Testing, Copy Number Variation, Sarcoma, Soft Tissue, Bone, MDM2, ISH | |
Anatomical Pathology | |
Surgical Pathology | |
Group Test: MDM2GF
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Other Information
In-house: Reflex test following 2+ HER2 IHC score.
Assessment of gene amplification (e.g. MDM2)
Biomarkers: FISH/Copy Number Variation
MDM2 FISH, where indicated, aids in classification, prognostic assessment, and therapeutic purposes.
Biomarkers: FISH/Copy Number Variation
MDM2 FISH, where indicated, aids in classification, prognostic assessment, and therapeutic purposes.
Formalin fixed paraffin embedded block or tissue sections cut at 4 microns mounted on charged or coated slides.
Fixation between 6-72 hours
Room temperature (block/unstained slide)
Dako Omnis
Monday to Friday; 8 am - 4 pm
Typically 7 days, with a maximum of 14 days
Please refer directly to the Pathology Report
416-586-4800 Extension 4481 or 3813
Fax: (416) 586-8628
Email: PLMconsults@sinaihealth.ca
Fax: (416) 586-8628
Email: PLMconsults@sinaihealth.ca
Typically used to query well-differentiated liposarcoma (WDLPS), atypical lipomatous tumour (ALT), or dedifferentiated liposarcoma (DDLPS).
Ontario Health: See Sarcoma Program
https://www.cancercareontario.ca/en/guidelines-advice/treatment-modality/pathology-laboratory-testing/genetic-testing-resources
https://www.cancercareontario.ca/en/guidelines-advice/treatment-modality/pathology-laboratory-testing/genetic-testing-resources