Thrombin converts fibrinogen in plasma into fibrin forming a clot. Thrombin time is a screening coagulation test designed to assess fibrin formation from fibrinogen in plasma.
The 9:1 blood/citrate ratio must be kept constant. Adjustments for the amount of anticoagulant should be made when the hematocrit is abnormal (above 55%). Mix immediately to prevent clotting.
Collection Instructions
Send whole blood sample(s) at room temperature as soon as possible.
If specimens cannot be shipped immediately, centrifuge and separate plasma within 1 hour of collection, send frozen plasma on dry ice
Adult: 14.0-21.0 sec
Full-term Infant at Birth: 19.0 – 28.3 sec
Premature Infant of 30 to 36 Weeks gestational age: 19.2-30.4 sec In case of discrepancies, always interpret results using reference ranges as stated on laboratory reports and/or electronic patient chart.