Thyroglobulin Antibodies

Alternative Names/Synonyms	Anti-TG, ATG
Laboratory	Core Laboratory & Transfusion Medicine
Sub-section	Biochemistry
Specimen Type	Blood
Test Code	ATGS

Clinical Significance (If applicable)

Evaluating thyroglobulin assay interference (false positives) in thyroid cancer patients.

Evaluating Hashimoto's thyroiditis although testing alongside Anti-TPO may be redundant.

Specimen Requirements (Sample Type)

Serum

Specimen Requirements (Volume (mL))

0.5 mL

Specimen Requirements (Tube Type)

Serum (Gold SST)
Collection Containers – Tube Types

Draw (mL)

4.5 mL

Collection Requirements

Collection Instructions

Sample Stability

Room Temperature: N/A

Fridge: 3 days @ 2-8°C

Freezer: 1 month @ -20°C

Cause for Rejection

Specimen Acceptability and Transport Guidance

Instrument, Methodology

Roche cobas e 602, immunoassay

Test Availability

24 hours a day, 7 days a week

STAT Turnaround Time

1 hour

Routine Turnaround Time

3 hours

Reference Ranges

Interference with Thyroglobulin measurement:
Does not interfere: ≤ 22 kIU/L
Does interfere: > 22 kIU/L

Hashimoto’s Thyroiditis:
Negative: ≤ 115 kIU/L
Positive: > 115 kIU/L

In case of discrepancies, always interpret results using reference ranges as st

Laboratory Contact Information

416-586-4800 extension 4688