Thyroid Cancer Panel

Alternative Names/Synonyms	SGT, Somatic Genetic Testing, BRAF, HRAS, KRAS, NRAS, NTRK3, PPARG, RET
Laboratory	Diagnostic Medical Genetics
Sub-section	Advanced Molecular Genetics
Specimen Type	Fixed Tissue - Formalin Fixed Paraffin Embedded
Test Code	M2TDD1, M2TDR2

Ordering Instructions, Requisition

https://www.mountsinai.on.ca/care/pathology/laboratory-forms-and-requisitions/pathology-consult-requisition/view

Supporting Documents

Somatic Genetic Testing Reference Sequences

Clinical Significance (If applicable)

Please refer to Genetic Testing Program | Cancer Care Ontario

https://www.cancercareontario.ca/en/guidelines-advice/treatment-modality/pathology-laboratory-testing/genetic-testing-resources

Specimen Requirements (Sample Type)

Formalin Fixed Paraffin Embedded Tissue Block

Specimen Requirements (Volume (mL))

Blocks are preferred.

If submitting slides:
6 x 10um on plain slides + 1 H&E AND 10um curls. Super Clean cutting in 1.5 mL tube

ParaffinSections

Collection Requirements

See Instructions on Cutting Slides for Genetic Tests

Storage / Shipment Details

Room Temperature. Must not be refrigerated frozen or exposed to heat.

Cause for Rejection

Specimen Acceptability and Transport Guidance

Test Availability

Routine only; Monday to Friday

Routine Turnaround Time

2 weeks

Laboratory Contact Information

molecularlab.MSH@sinaihealth.ca

Gene(s)

BRAF, HRAS, KRAS, NRAS, NTRK3, PPARG, RET

Sample Processing / Delivery

Samples received and processed Monday to Friday 8:00 am - 5:00 pm

Funded for patients with OHIP

Yes

Disease/Body Site

Thyroid; Indications outlined by Ontario Health (formerly Cancer Care Ontario); see link in Clinical Significance section

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