Tissue Transglutaminase Antibodies, IgG

Alternative Names/Synonyms	Anti-Tissue Transglutaminase Antibody, tTG IgG
Laboratory	Core Laboratory & Transfusion Medicine
Sub-section	Biochemistry
Specimen Type	Blood
Test Code	TTIGG

Clinical Significance

Aiding in the diagnosis of Celiac disease and dermatitis herpetiformis, and monitoring response to a gluten-free diet in IgA-deficient patients.

Specimen Requirements (Sample Type)

Serum

Specimen Requirements (Volume (mL))

0.5 mL

Specimen Requirements (Tube Type)

Serum (Gold SST)
Collection Containers – Tube Types

Collection Requirements

Blood Collection Instructions

Sample Stability

Room Temperature: 2 Weeks

Fridge: 8 weeks @ 2-8°C

Freezer: 1 year @ -20°C

Cause for Rejection

Specimen Acceptability and Transport Guidance

Instrument, Methodology

BIO-FLASH, immunoassay

Test Availability

Weekdays

Routine Turnaround Time

1 week

Reference Ranges

Negative: < 20 CU
Weak Positive: 20 - 30 CU
Positive: > 30 CU

In case of discrepancies, always interpret results using reference ranges as stated on laboratory reports and/or electronic patient chart.

Laboratory Contact Information

416-586-4800 extension 4688