von Willebrand Disease Investigation

VWD, VWD Investigation, von Willebrand Screen
Core Laboratory & Transfusion Medicine
Hematology
Blood
VWDI

MSH Coagulation requisition form (MS 520)

Von Willebrand Disease (VWD) is the most common inherited bleeding disorder. Clinically, it is often characterized by muco-cutaneous hemorrhages. The Group test includes Factor VIII Assay, vWF Activity and Antigen.

Plasma (3.2% Na Citrate)

Full draw

Light Blue citrate tube
Collection Containers – Tube Types

The 9:1 blood/citrate ratio must be kept constant. Adjustments for the amount of anticoagulant should be made when the hematocrit is abnormal (above 55%). Mix immediately to prevent clotting.
Collection Instructions

Send whole blood sample(s) at room temperature as soon as possible.
If specimens cannot be shipped immediately, centrifuge and separate plasma within 1 hour of collection, send frozen plasma on dry ice

8 hrs at Room Temperature, 12 months at -70ºC or below.


Automated Coagulation Analyzer

Test may be requested at any time. Samples are aliquotted and frozen. The assay is run in batches.

Special arrangements made with Lab

1-2 weeks

See individual ranges and values for Factor VIII Assay, vWF Activity and Antigen. In case of discrepancies, always interpret results using reference ranges as stated on laboratory reports and/or electronic patient chart.

416-586-4800 Extension 4688

Must indicate anticoagulant status